Distribution of CSF1PO TPOX and TH01 loci in five minority populations in Yunnan of China / 中华医学遗传学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the distribution of CSF1PO, TPOX and TH01 in 5 minority populations only resided in Yunnan province.</p><p><b>METHODS</b>DNA extraction from bloods and multiplex amplification of CSF1PO, TPOX and TH01 were carried out. The technique of denaturing polyacrylamide gel electrophoresis and silver staining method were used.</p><p><b>RESULTS</b>The data on the distribution of allele frequencies of 3 loci(CSF1PO, TPOX and TH01) in Achang Deang Bulang Pumi and Jino were collected and analyzed.</p><p><b>CONCLUSION</b>The allele distribution of the loci were in good agreement with the Hardy-Weinberg equibrium. A satisfactory result was obtained and some significant genetics differences were noticed in different populations.</p>