Genetic polymorphism analysis of 8 short tandem repeat loci on the X chromosome in Luoba population of China / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 479-481, 2007.
Article
em Zh
| WPRIM
| ID: wpr-247286
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the alleles and genotype frequency of 8 short tandem repeat (STR) loci (DXS6804, DXS8378, DXS7132, DXS7133, DXS6789, DXS101, HPRTB and DXS7423) on the X chromosome in Luoba ethnic group of China.</p><p><b>METHODS</b>The eight X chromosome STR (X-STR) loci were analyzed by polymerase chain reaction (PCR) followed by polyacylamide gel electrophoresis and silver stain.</p><p><b>RESULTS</b>Among 96 unrelated Luoba individuals, the numbers of alleles in the 8 X-STR loci (DXS7133, DXS6789, DXS6804, DXS8378, DXS101, DXS7424, DXS7132 and HPRTB) were 5, 8, 7, 5, 8, 8, 8 and 5, respectively. The genotype frequencies in females were in accordance with Hardy-Weinberg equilibrium.</p><p><b>CONCLUSION</b>The eight X-STR loci are appropriate for individual identification, paternity testing involving a female child and studies on related diseases.</p>
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Base de dados:
WPRIM
Assunto principal:
Polimorfismo Genético
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China
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Reação em Cadeia da Polimerase
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Repetições de Microssatélites
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Cromossomos Humanos X
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Frequência do Gene
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Genética
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Genética Populacional
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Genótipo
Limite:
Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2007
Tipo de documento:
Article