Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To probe the relationship between serum HBV DNA levels and serum hyaluronic acid (HA) levels in hepatitis B cirrhosis patients.</p><p><b>METHODS</b>Of 62 patients diagnosed with hepatitis B cirrhosis serum HBV DNA was determined by fluorescent quantitative PCR. Serum HA was determined by radioimmunity assay. The relationship between serum HBV DNA levels and serum HA levels was probed.</p><p><b>RESULTS</b>Serum HA of hepatitis B cirrhosis patients increased significantly and increased with the Child grade ascending (P less than 0.05). But serum HA levels had no significant correlation with serum HBV DNA levels (P greater than 0.05).</p><p><b>CONCLUSION</b>Serum HBV DNA levels had no significant correlation with liver cirrhosis grades and serum HA levels in hepatitis B cirrhosis patients.</p>