Advances in the study of the anti-tumor activity of small molecule vascular disrupting agents / 药学学报
Acta Pharmaceutica Sinica
; (12): 283-288, 2010.
Article
em Zh
| WPRIM
| ID: wpr-250590
Biblioteca responsável:
WPRO
ABSTRACT
Vascular disrupting agents (VDAs) have presented a new kind of anti-cancer drug in recent years. VDAs take advantage of the weakness of established tumor endothelial cells and their supporting structures. In contrast to anti-angiogenic therapy, which inhibits the outgrowth of new blood vessels, vascular targeting treatments selectively attack the existing tumor vasculature. Here we summarized the anti-tumor activities, mechanisms and clinical applications of small molecule VDAs.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Oligopeptídeos
/
Compostos Organofosforados
/
Patologia
/
Farmacologia
/
Serina
/
Estilbenos
/
Bibenzilas
/
Estrutura Molecular
/
Química
/
Difosfatos
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2010
Tipo de documento:
Article