A Case of IgA Nephropathy Associated with Systemic Lupus Erythematosus / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
; : 54-58, 2009.
Article
em Ko
| WPRIM
| ID: wpr-26851
Biblioteca responsável:
WPRO
ABSTRACT
Renal involvement is frequently seen in patients with systemic lupus erythematosus (SLE). The occurrence of non-lupus nephritis, and especially IgA nephropathy, in SLE patients has rarely been reported. We describe here the case of a 30-year-old woman who had systemic lupus erythematosus and nontuberculous mycobacterial lung disease, and her biopsy of a renal lesion was unexpectedly diagnostic of IgA nephropathy. Although both IgA nephropathy and lupus nephritis are immune complex mediated diseases, their laboratory and histopathologic findings and the extra-renal clinical manifestations are different and these all support a different pathogenesis for the 2 diseases. Renal biopsy plays a crucial role in identifying and diagnosing renal lesions, which may have prognostic and therapeutic implications that are distinct from those of lupus nephritis. In conclusion, performing a renal biopsy in SLE patients who have urinary abnormalities is important since a correct diagnosis would permit the most appropriate treatment to be started and so avoid unnecessary immunosuppressive treatments.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Biópsia
/
Nefrite Lúpica
/
Imunoglobulina A
/
Glomerulonefrite por IGA
/
Pneumopatias
/
Lúpus Eritematoso Sistêmico
/
Complexo Antígeno-Anticorpo
/
Nefrite
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
Ko
Revista:
The Journal of the Korean Rheumatism Association
Ano de publicação:
2009
Tipo de documento:
Article