Determination of phillyrin and forsythoside A in Lianqiao Bingdu Qing capsule by RP-HPLC / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 36-39, 2005.
Article
em Zh
| WPRIM
| ID: wpr-276650
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ABSTRACT
<p><b>OBJECTIVE</b>To establish methods for the determination of phillyrin and forsythoside A in Lianqiao Bingdu Qing capsule by RP-HPLC.</p><p><b>METHOD</b>The determination of phillyrin was carried out on YWG-C18 column (4.6 mm x 250 mm, 10 microm), using acetonitrile-water (2575) as mobile phase at a flow rate of 0.8 mL x min(-1) and detected at the wavelength 277 nm. The determination of forsythoside A was carried out with YWG-C18 column(4.6 mm x 250 mm,10 microm), using acetonitrile-water-Acetic acid (17830.4) as mobile phase at a flow rate of 1.0 mL x min(-1) and detected at the wavelength 280 nm.</p><p><b>RESULT</b>The average recovery of phillyrin was 99.6%, RSD = 1.9% (n = 5). The average recovery of forsythoside A was 101.3%, RSD = 2.5% ( n = 5).</p><p><b>CONCLUSION</b>The methods were simple and accurate and could be used to control the quality of the Lianqiao Bingdu Qing capsule.</p>
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Base de dados:
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Assunto principal:
Plantas Medicinais
/
Cápsulas
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Medicamentos de Ervas Chinesas
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Química
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Cromatografia Líquida de Alta Pressão
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Forsythia
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Frutas
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Glucosídeos
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Glicosídeos
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Métodos
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2005
Tipo de documento:
Article