Application of a new design of cryo-jaw and its biomechanical evaluation in rat achilles tendon in vitro / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 678-681, 2014.
Article
em Zh
| WPRIM
| ID: wpr-290694
Biblioteca responsável:
WPRO
ABSTRACT
This study was aimed to design a new, accurate and easy-to-use water bath cryo-jaw, and try to solve the problems met in small animals achilles tendon mechanical testing. The muscle-tendon-bony units were fixed in the clamps. SD rats achilles tendon were randomly divided into group A and B. Group A was tested by the newly designed water bath cryo-jaw, while group B was treated by non-water bath cryo-jaw. The mechanical tests revealed that non of the samples of the newly-designed water bath cryo-jaw in group A slipped and fell off, and the achilles tendons were in a physiologically active state, but one of the group B samples slipped and fell off, and the others had the frozen phenomenon obviously. The maximum stress, fracture displacement and Young's modulus of the rats in group A were significantly different compared to those in group B (P < 0.05). In conclusion, the new water bath cryo-jaw has more advantages than traditional ones. It exhibits a good simulation in vivo in the environmental conditions for testing the mechanical properties of the achilles tendon.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fisiologia
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Tendão do Calcâneo
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Fenômenos Biomecânicos
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Técnicas In Vitro
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Ratos Sprague-Dawley
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Desenho de Equipamento
/
Módulo de Elasticidade
Limite:
Animals
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2014
Tipo de documento:
Article