Studies on chemical constituents of Sarcandra glabra / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 900-902, 2008.
Article
em Zh
| WPRIM
| ID: wpr-295445
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study antibacterial chemical constituents of Sarcandra glabra.</p><p><b>METHOD</b>The constituents of the chloroform and EtOAc-soluble portions of the EtOH extract from the whole plant of S. glabra, which posses the antibacterial activities, were isolated and purified with column chromatography. The compounds were identified by physical and spectroscopic techniques.</p><p><b>RESULT</b>Six compounds were isolated and identified as 4, 4'-biisofraxidin (1), esculetin (2), fraxetin (3), scoparone (4), isofraxidin (5), scopoletin(6), respectively.</p><p><b>CONCLUSION</b>Compound 1 is a novel natural product. Compounds 24 were isolated from the plants of Chloranthaceae for the first time. The antibacterial activities of these six compounds were tested for the first time. Some compounds may have potential for future study and development as plant-derived oral antibacterial agents.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Farmacologia
/
Espectrofotometria Infravermelho
/
Streptococcus mutans
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Medicamentos de Ervas Chinesas
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Espectroscopia de Ressonância Magnética
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Química
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Porphyromonas gingivalis
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Magnoliopsida
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Cumarínicos
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Espectrometria de Massas por Ionização por Electrospray
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2008
Tipo de documento:
Article