Epigenetics and neural stem cell commitment / 神经科学通报·英文版
Neuroscience Bulletin
; (6): 241-248, 2007.
Article
em En
| WPRIM
| ID: wpr-300957
Biblioteca responsável:
WPRO
ABSTRACT
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refer to the study of mitotical/meiotical heritage changes in gene function that cannot be explained by changes in the DNA sequence. Major epigenetic mechanisms include DNA methylation, histone modification, chromatin remodeling, genomic imprinting, and non-coding RNA. In this review, we focus on the new insights into the epigenetic mechanism for neural stem cells fate.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fisiologia
/
Células-Tronco
/
Diferenciação Celular
/
Impressão Genômica
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Metilação de DNA
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Montagem e Desmontagem da Cromatina
/
Epigênese Genética
/
Neurônios
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Neuroscience Bulletin
Ano de publicação:
2007
Tipo de documento:
Article