Effect of Bushen Yiqi Hexue recipe on endometrial P21 expression of embryo implantation dysfunctional mice / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2152-2155, 2007.
Article
em Zh
| WPRIM
| ID: wpr-307489
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of Bushen Yiqi Hexue recipe on endometrial P21 and PCNA expression of embryo implantation dysfunctional mice.</p><p><b>METHOD</b>The expression of P21 protein was analyzed by means of immunoblot and immunohistochemical method. The expression of PCNA protein was analyzed by means of immunohistochemical method.</p><p><b>RESULT</b>The expression and disappearance of P21 and PCNA protein in endometrium of embryo implantation dysfunctional mice lagged behind in a temporal and cell specific manner. Bushenyiqihexue recipe could improve the expression of P21 and PCNA protein in a temporal and cell specific manner, and then improve the decidual reaction of endometrium of embryo implantation dysfunctional mice.</p><p><b>CONCLUSION</b>Improving the expression of P21 and PCNA protein in endometrium and eventually regulating endometrium decidual reaction is one of the mechanisms of improved embryo implantaion by Bushen Yiqi Hexue recipe.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Implantação do Embrião
/
Farmacologia
/
Fisiologia
/
Plantas Medicinais
/
Medicamentos de Ervas Chinesas
/
Imuno-Histoquímica
/
Immunoblotting
/
Química
/
Antígeno Nuclear de Célula em Proliferação
/
Combinação de Medicamentos
Limite:
Animals
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2007
Tipo de documento:
Article