Genetic polymorphism of 9 STR loci in Korean population of Mudanjiang / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
; (6): 348-351, 2008.
Article
em Zh
| WPRIM
| ID: wpr-308033
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the genetic polymorphism of 9 short tandem repeats (STR) gene loci, namely CSFIPO, TPOX, TH01, D16S539, D7S820, D13S317, F13A01, FESFPS and vWA in Chinese Korean population in Mudajiang area.</p><p><b>METHODS</b>Amplified fragment length polymorphism (Amp-FLP) method was used to get the allele frequency distribution.</p><p><b>RESULTS</b>The genotype distributions of the 9 STR loci are conformed to Hardy-Weinberg equilibrium by chi(2) test analysis. The total accord frequency, the accumulated total discrimination power and the the accumulative excluding probability of paternity were calculated.</p><p><b>CONCLUSION</b>The result suggested that all 9 gene loci have high power of excluding probability of paternity and individual identification. They can be used in paternity testing and individual identification for forensic medicine. The gene frequencies of CSFIPO, TPOX and TP01 gene loci have significant differences between the Korean population in Mudanjiang area and those in Yanji area, but there is no difference in gene loci of D7S820, D17S317 and vWA.</p>
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Base de dados:
WPRIM
Assunto principal:
Polimorfismo Genético
/
Repetições de Microssatélites
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Povo Asiático
/
Análise do Polimorfismo de Comprimento de Fragmentos Amplificados
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Genética
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Coreia (Geográfico)
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Medical Genetics
Ano de publicação:
2008
Tipo de documento:
Article