Stable life predection for honeysuckle by initial average rate stability test / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the content change of chlorogenic acid in honeysuckle under different temperature, and predict its term of validity at room temperature.</p><p><b>METHOD</b>The content of chlorogenic acid was assayed by HPLC. The activation energy E(a) and the decomposition rate constant K were calculated by initial average rate stability tests and the prediction was carried out.</p><p><b>RESULT</b>The stable life of honeysuckle has been determined as 1.29 years.</p><p><b>CONCLUSION</b>The initial average rate stability test was used to predict stable life of honeysuckle, and the results are credible. Higher temperature should be avoided for honeysuckle store, and room temperature should guarantee its quality during storage.</p>