Preliminary study of assessment of mental health level among oral tumor patients and difference of relevant material basis / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 45-50, 2014.
Article
em Zh
| WPRIM
| ID: wpr-315877
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the difference in mental health status of oral tumor patients and their spouses, and explore the differences on the basis of relevant materials.</p><p><b>METHODS</b>Forty patients with oral cancer, eighteen spouses, and thirty-five patients with oral benign tumor were diagnosed in the West China Hospital of Stomatology between December 2011 and August 2012 and assessed with symptom checklist-90 (SCL90) (the 5-grade scoring). Participants were assessed independently according to their conditions. Blood samples were obtained from the participants by syringe on the second admission day. A method was developed to determine the concentrations of catecholamine and glucocorticoid in the serum using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).</p><p><b>RESULTS</b>The scores for compel, depression and rests in the cancer group and benign tumor group were statistically significant (P<0.05). The scores for compel, dread and stubborn in the cancer group and their spouses were statistically significant (P<0.05). The differences between the total and other monomial factor scores were not statistically significant. However, the contents of epinephrine, norepinephrine, cortisone and hydrocortisone in the serum, as determined by HPLC-MS/MS, were significantly different (P<0.001).</p><p><b>CONCLUSION</b>Psychiatric factors do not show a simple factor effect on patients. Symptoms of patients may be based on tumorigenesis and developed in small molecules. Further research is required.</p>
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Neoplasias Bucais
/
Biomarcadores
/
China
/
Nível de Saúde
/
Saúde Mental
/
Espectrometria de Massas em Tandem
/
Neoplasias
Aspecto:
Determinantes_sociais_saude
/
Patient_preference
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
West China Journal of Stomatology
Ano de publicação:
2014
Tipo de documento:
Article