Research advances on associated genes and pathogenesis of hydrocephalus / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 644-649, 2010.
Article
em Zh
| WPRIM
| ID: wpr-319844
Biblioteca responsável:
WPRO
ABSTRACT
Hydrocephalus is a common medical condition characterized by abnormalities in the secretion,circulation or resorption of cerebrospinal fluid (CSF), resulting in ventricular dilatation. The pathogenetic mechanism for the hydrocephalus is attributed to the overproduction of CSF by the choroid plexus; the defect in CSF absorption and obstruction of CSF flow in the cerebral ventricles. However, the underlying etiology is poorly understood. With the development of genetic engineering, a growing body of evidence indicates that genetic factors play an essential role in the pathogenesis of hydrocephalus. It is the aim of this review to summarize these findings.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Patologia
/
Ventrículos Cerebrais
/
Camundongos Knockout
/
Modelos Animais de Doenças
/
Genética
/
Hidrocefalia
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2010
Tipo de documento:
Article