Optimal extraction of Dingxiang jiangqi granules / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To screen and optimize the extraction of Dingxiangjiangqi granules.</p><p><b>METHOD</b>The extraction route was screened by using pharmacodynamic experiment and the extraction conditions were optimized by orthogonal design and taking extract yield, content of naringin and tetrahydropalmatine as indexes.</p><p><b>RESULT</b>The pharmacodynamic result showed that aqueous extract had the best effect to cure the esophagitis of rats and the optimized extraction technique was adding 12 times water, extracting 0. 5 hour for 3 times.</p><p><b>CONCLUSION</b>The optimum extraction was simple, reasonable, stable and useful for further development.</p>