Advanced achievements about neuroprotective mechanisms of paeoniflorin / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1490-1493, 2010.
Article
em Zh
| WPRIM
| ID: wpr-328091
Biblioteca responsável:
WPRO
ABSTRACT
Paeoniflorin is one of the bioactive components of Paeonia lactiflora, a traditional Chinese herbal medicine. Some recent studies prove its distinguished neuroprotective effect. These neuroprotective mechanisms have become hot points and show closely correlated to activating adenosine A1 receptor, ameliorating the function of cholinergic nerve, regulating ion channel homeostasis, retarding oxidative stress and apoptosis of the neurocytes, promoting nerve growth, having an influence on astrocytes and being ableto penetrate though blood brain barrier. In this review, we present the neuroprotective mechanisms of paeoniflorin in the following eight aspects.
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Base de dados:
WPRIM
Assunto principal:
Farmacologia
/
Benzoatos
/
Hidrocarbonetos Aromáticos com Pontes
/
Medicamentos de Ervas Chinesas
/
Química
/
Apoptose
/
Estresse Oxidativo
/
Fármacos Neuroprotetores
/
Paeonia
/
Biologia Celular
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2010
Tipo de documento:
Article