Effective ways to improve the prognosis of advanced stage (BCLC stage C) hepatocellular carcinoma / 中华外科杂志
Chinese Journal of Surgery
; (12): 324-327, 2015.
Article
em Zh
| WPRIM
| ID: wpr-336634
Biblioteca responsável:
WPRO
ABSTRACT
Hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) or lymphatic/extrahepatic metastasis is classified as advanced stage (Stage C of Bacelona Clinic Liver Cancer Staging). There is few effective therapy for the advanced stage HCC, leading to an extremly poor prognosis. For these patients, Sorafinib is recommended as the only therapy by European and American guidelines, which has limited clinic effect. In China, besides Sorafinib, various therapies have also been suggested, including surgery, trans-arterial chemoembolization (TACE), radiotherapy, as well as traditional Chinese medicine. Recently, it is reported that several therapies may be effective in treating HCC with PVTT which is classified based on Cheng's classification, including surgery after "down-stage" radiotherapy, early use of sorafinib postoperatively, as well as postoperative antivirus treatment. The modified Folfox4 chemotherapy, is also a potential effective way to improve the prognosis of advanced stage HCC with lymphatic/extrahepatic metastasis. Mutiple disciplinary team which could faciliate the process of diagnosis and treatment of advanced stage HCC, is expected to favor the prognosis of these patients.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Veia Porta
/
Prognóstico
/
Terapêutica
/
Trombose
/
China
/
Resultado do Tratamento
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Quimioembolização Terapêutica
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Carcinoma Hepatocelular
/
Neoplasias Hepáticas
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Metástase Linfática
Tipo de estudo:
Guideline
/
Prognostic_studies
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Surgery
Ano de publicação:
2015
Tipo de documento:
Article