Apoptosis of epididymal epithelium and the content of epididymal carnitine following testicular torsion/detorsion in rats / 中华男科学杂志
National Journal of Andrology
; (12): 636-638, 2006.
Article
em Zh
| WPRIM
| ID: wpr-343554
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between the apoptosis of epididymal epithelium and the change of epididymal carnitine following testicular torsion/detorsion in rats.</p><p><b>METHODS</b>Twenty-four healthy adult male Sprague-Dawley rats were randomly divided into 3 groups: Group A (2-hr torsion), Group B (5-hr torsion) and a control group (0-hr torsion). The ipsilateral epididymides were collected for detecting the content of carnitine by DTNB technique and the apoptosis of epididymal epithelium by TUNEL technique.</p><p><b>RESULTS</b>Twenty-four hours after the treatment, there was no statistically significant difference in the apoptosis of epididymal epithelium and the content of epididymal carnitine between the 2-hr torsion/detorsion group and the control (P > 0.05). However, there was statistically significant difference in the apoptosis of epididymal epithelium and the content of epididymal carnitine between the 5-hr group and the control (P < 0.05).</p><p><b>CONCLUSION</b>Twenty-four hours after 2-hr testicular torsion/detorsion, the carnitine-concentrating function of the epididymis may remain normal and the apoptosis index of epididymal epithelium does not increase significantly, while one day after 5-hr testicular torsion/detorsion, the apoptosis index increases and the carnitine-concentrating function decreases.</p>
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Base de dados:
WPRIM
Assunto principal:
Patologia
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Torção do Cordão Espermático
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Cirurgia Geral
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Carnitina
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Distribuição Aleatória
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Ratos Sprague-Dawley
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Apoptose
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Epididimo
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Células Epiteliais
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Metabolismo
Limite:
Animals
Idioma:
Zh
Revista:
National Journal of Andrology
Ano de publicação:
2006
Tipo de documento:
Article