Lipoprotein (a) and cerebral infarction in young adults / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 397-400, 2003.
Article
em Zh
| WPRIM
| ID: wpr-348858
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relation between lipoprotein (a) (LP(a)) and cerebral infarction in young adults.</p><p><b>METHODS</b>Serum LP(a) of 90 young adults (age below 45 years) with cerebral infarction was measured. Serum lipids include triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein A-I (ApoA-I) and apolipoprotein B (ApoB) were also measured. Other possible risk factors such as hypertension, smoking, drinking and family stroke history were reviewed.</p><p><b>RESULTS</b>There was no significant difference of serum LP(a) value between stroke patients and controls. TG (P < 0.01) and ApoB (P < 0.01) values in patients with cerebral infarction were significant higher than those in controls. Lipoprotein (a) was correlated with total cholesterol and low density lipoprotein cholesterol, with the values of correlation coefficient (r) 0.28 and 0.23 (both P < 0.01). After adjustment for age, sex, hypertension, smoking, drinking alcohol, family stroke history and other serum lipids, the odd radio for LP(a) and cerebral infarction was 0.74 (95% CI 0.27 - 1.98). The odd radio for elevated TG was 3.57 (95% CI 1.34 - 9.49); The odd ratios for hypertension, heart diseases and smoking as risk factors for cerebral infarction in young patients showed as hypertension OR = 8.18, 95% CI 2.54 - 26.33; heart diseases OR = 8.51, 95% CI 2.27 - 31.85; smoking OR = 3.21, 95% CI 1.27 - 8.13.</p><p><b>CONCLUSION</b>LP(a) might not be a risk factor for cerebral infarction in young patients while elevated triglyceride, hypertension, heart diseases and smoking were important risk factors in young adults with cerebral infarction.</p>
Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Triglicerídeos
/
Sangue
/
Fumar
/
Modelos Logísticos
/
Infarto Cerebral
/
China
/
Epidemiologia
/
Fatores de Risco
/
Fatores Etários
/
Lipoproteína(a)
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2003
Tipo de documento:
Article