Coexpression of Schwann cell marker GFAP and myoepithelial cell marker alpha-SMA in salivary adenoid cystic carcinoma / 中华口腔医学杂志
Chinese Journal of Stomatology
; (12): 461-463, 2006.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-354344
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the expression of Schwann cell marker GFAP and myoepithelial cell marker alpha-SMA in salivary adenoid cystic carcinoma (ACC), and to evaluate the relationship of GFAP, alpha-SMA and perineural invasion in ACC.</p><p><b>METHODS</b>Immunohistochemical SABC method, double-label immunofluorescence and CLSM were used to detect the expression of GFAP and alpha-SMA proteins in salivary ACC tissue samples.</p><p><b>RESULTS</b>In salivary ACC tissue samples, both GFAP and alpha-SMA proteins were positive, which were coexpressed in cytoplasm of the same onco-myoepithelial cells.</p><p><b>CONCLUSIONS</b>There may be Schwann cell differentiation in onco-myoepithelial cell of salivary ACC, and it may be the pathological base of perineural invasion in salivary ACC.</p>
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Células de Schwann
/
Neoplasias das Glândulas Salivares
/
Actinas
/
Carcinoma Adenoide Cístico
/
Células Musculares
/
Células Epiteliais
/
Proteína Glial Fibrilar Ácida
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2006
Tipo de documento:
Artigo