Protective effect of purariae isoflavone on apoptosis cells of nasal mocosas in ovariectomized rats / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 855-857, 2005.
Article
em Zh
| WPRIM
| ID: wpr-358069
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the protective effect of purariae isoflavone on apoptosis cells of atrophic nasal mucosas in ovariectomized rats.</p><p><b>METHOD</b>60 rats were divided into four groups as control, ovariectomized, ovariectomized + nylestriol (O + N) and ovariectomized + purariae isoflavone (O + P), each with 15 rats. Earlier apotosis cells of mucosas taken from nasal septum were measured with flow cytometry.</p><p><b>RESULT</b>Compared with control group, and the number of apoptosis cells of mucosas increased after being ovariectomized,and the number of apoptosis cells of mucosas in O + N and O + D group didn't change.</p><p><b>CONCLUSION</b>Nylestriol and purariae isoflavone might have effects on protecting cells of mucosas from lacking of estrogen by decreasing apoptosis cells in ovariectomized rats.</p>
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Base de dados:
WPRIM
Assunto principal:
Patologia
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Farmacologia
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Plantas Medicinais
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Quinestrol
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Ovariectomia
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Química
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Ratos Sprague-Dawley
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Apoptose
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Substâncias Protetoras
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Pueraria
Limite:
Animals
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2005
Tipo de documento:
Article