Farnesoid X receptor dependent bile acid signaling regulates bile acids metabolism / 国际外科学杂志
International Journal of Surgery
; (12): 565-568, 2008.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-399180
Biblioteca responsável:
WPRO
ABSTRACT
The Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and has emerged as a key player in the control of multiple metabolic pathways. Bile acids are the major endogenous ligands for FXR, and by activating FXR have a variety of target genes, many of which are geared toward pre- venting synthesis and uptake and promoting excretion of bile acids. Here we summarized the latest results from studies on FXR target genes and functions in bile acids metabolism in this article.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
International Journal of Surgery
Ano de publicação:
2008
Tipo de documento:
Artigo