Inhibition of Newcastle disease virus (NDV) replication by RNA interference targeting phosphoprotein (P) gene in CEF / 中国兽医学报
Chinese Journal of Veterinary Science
; (12): 841-844, 2009.
Article
em Zh
| WPRIM
| ID: wpr-406352
Biblioteca responsável:
WPRO
ABSTRACT
A plasmids of continuous expressing shRNAs targeting the NDV NA-1 Phosphoprotein (P) gene was designed.Virus titration,Real Time RT-PCR,CPE indicated that P-specific siRNA could inhibit virus replication at 36 h post-virus infection.In future studies,a combination of siRNAs targeting the NP and L gene may be used as a tool to study NDV replication and antiviral therapy.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Veterinary Science
Ano de publicação:
2009
Tipo de documento:
Article