β-cell function of subjects with 1-hour hyperglycemia in oral glucose tolerance test / 中华全科医师杂志
Chinese Journal of General Practitioners
; (6): 827-829, 2011.
Article
em Zh
| WPRIM
| ID: wpr-422734
Biblioteca responsável:
WPRO
ABSTRACT
Based on the results of oral glucose tolerance test( OGTT )and the levels of 1-h plasma glucose ( 1 hPG),793 subjects were classified into three groups583 with NGTN ( normal 1 hPG in OGTT),127 with NGT1 H( higher 1 hPG in OGTT) and 83 with IGT( impaired glucose tolerance).NGT1H group had large waist circumference,higher body mass index,fasting plasma glucose( FPG),triglyceride,and lower high density lipoprotein-cholesterol than those of NGTN group.NGT1 H group had higher homeostasis model assessment insulin index ( 1.2 ± 0.6),lower homeostasis model assessment β3 ( HOMA-β ) (4.5 ± 0.7 ) and insulinogenic index (2.1 ±0.7) than those of NGTN group(0.5 ±0.6,4.8 ±0.7,2.7 ±0.9,respectively,all P <0.05 ).HOMA-β of NGT1 H group was higher than that of IGT group(4.5 ±0.7 vs.4.4 ±0.6,P <0.05 ).The results indicate that 1 hPG in OGTT may identify a condition of glucose metabolic abnormalities characterized by insulin resistance and reduced β-cell function.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of General Practitioners
Ano de publicação:
2011
Tipo de documento:
Article