Effects of ceramide-induced apoptosis on oncotherapy / 国际肿瘤学杂志
Journal of International Oncology
; (12): 811-814, 2013.
Article
em Zh
| WPRIM
| ID: wpr-439089
Biblioteca responsável:
WPRO
ABSTRACT
Ceramide (Cer),as the center molecular of sphingolipids metabolism,functions as a bioactive mediator of different cellular processes,such as cell growth,differentiation,senescence and apoptosis,besides being structural component of cellular membrane.It can inhibit cell proliferation and promote cell apoptosis via multiple signal pathawys.Chemicals anti-cancer properties based on Cer metabolism that upregulate its level are confirmed in plenty of experimental researches,and parts of research productions are applied in anticancer clinic experiments.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2013
Tipo de documento:
Article