Effect of blood glucose control level on prognosis in cerebral infarction with stress hyperglycemia / 中国医师进修杂志

ABSTRACT

Objective To analyze the effect of blood glucose control level on prognosis in cerebral infarction with stress hyperglycemia.Methods Ninety-two cases of new cerebral infarction within 24 h with stress hyperglycemia were divided into control group (46 cases) and observation group (46 cases).The blood glucose was controlled in 4.0-6.0 mmol/L in control group and 6.1-8.3 mmol/L in observation group.The hypoglycemia rate,infection rate,fatality rate,NIHSS score and Barthel score was observed in two groups.Results In control group,there were 14 cases cured,19 cases significantly improved,12 cases improved and 1 case invalid,while in observation group,there were 11,17,15,3 cases respectively,and the difference was not statisticly significant (P ＞ 0.05).The hypoglycemia rate,infection rate,fatality rate was 19.6％(9/46),10.9％(5/46) and 2.2％(1/46) respectively in control group,while in observation group was 4.3％ (2/46),15.2％ (7/46) and 4.3％ (2/46) respectively.The hypoglycemia rate was different between two groups(P ＜ 0.05),but the infection rate and fatality rate was not statistic difference between two groups(P ＞0.05).The NIHSS and Barthel score was not different between two groups before treatment (P ＞ 0.05).In control group the NIHSS after 1 week and 30 days after treatment and Barthel score 30 days after treatment was (15.47 ± 7.78),(9.85 ± 6.47),(67.18 ± 20.24) scores respectively,in observed group was (16.01 ±7.49),(10.17 ±5.84),(65.82 ± 19.93) scores respectively,which was improved compared with that pretreatment,but there was no significant difference between two groups(P ＞ 0.05).Conclusion The blood glucose controlled in 6.1-8.3 mmol/L does not increase the infection rate and fatality rate,but can reduce the hypoglycemia rate and promote neural function recovery in cerebral infarction with stress hyperglycemia.