Genetic Polymorphism in Proteins of the Complement System / 대한이식학회지
The Journal of the Korean Society for Transplantation
; : 59-68, 2016.
Article
em Ko
| WPRIM
| ID: wpr-45804
Biblioteca responsável:
WPRO
ABSTRACT
The complement system is a part of the innate immune system that potentiates the ability of antibodies and phagocytic cells to clear microbes and damaged cells. The complement system consists of a number of proteins circulating as inactive precursors. It is stimulated mainly by three pathways: the classical pathway, the alternative pathway, and the lectin pathway. There are many genetic polymorphisms in this system, which can over-activate the immune system. In this study, we collected the polymorphisms reported to over-activate complement cascades that affect the immune system and induce autoimmune diseases.
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Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Fagócitos
/
Polimorfismo Genético
/
Doenças Autoimunes
/
Proteínas do Sistema Complemento
/
Sistema Imunitário
/
Anticorpos
Idioma:
Ko
Revista:
The Journal of the Korean Society for Transplantation
Ano de publicação:
2016
Tipo de documento:
Article