Research progress of ERCC1 in non-small cell lung cancer based on the platinum drugs / 国际肿瘤学杂志
Journal of International Oncology
; (12): 909-912, 2014.
Article
em Zh
| WPRIM
| ID: wpr-458827
Biblioteca responsável:
WPRO
ABSTRACT
Excision repair cross complementing group 1 (ERCC1) gene is an enzyme of the speed limit of DNA repair protein in nucleotide excision repair (NER) pathways.Researches suggest that ERCC1 has been associated with cisplatin resistance in non-small cell lung cancer (NSCLC) patients.Thus,ERCC1 gene is a new target in malignant tumor gene therapy research,providing a new approach for the treatment of malignant,especially NSCLC.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2014
Tipo de documento:
Article