Acute pancreatitis associated with pegylated interferon-alpha-2a therapy in chronic hepatitis C
Clinical and Molecular Hepatology
; : 168-171, 2016.
Article
em En
| WPRIM
| ID: wpr-46327
Biblioteca responsável:
WPRO
ABSTRACT
Chronic hepatitis C virus (HCV) infection is a major cause of liver cirrhosis and hepatocellular carcinoma. Combination therapy of pegylated interferon-alpha (PEG-IFN-α) and ribavirin (RBV) is a current standard treatment for chronic HCV infection in Korea, which has considerable adverse effects. Acute pancreatitis is a rare complication of PEG-IFN-α administration. We report a case of a 62-year-old female who experienced acute pancreatitis after 4 weeks of PEG-IFN-α-2a and RBV combination therapy for chronic HCV infection. The main cause of the acute pancreatitis in this case was probably PEG-IFN-α rather than RBV for several reasons. A few cases have been reported in which acute pancreatitis occurred during treatment with PEG-IFN-α-2b. This is the first report of acute pancreatitis associated with PEG-IFN-α-2a in Korea.
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Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Antivirais
/
Pancreatite
/
Polietilenoglicóis
/
Ribavirina
/
Proteínas Recombinantes
/
Tomografia Computadorizada por Raios X
/
Interferon-alfa
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Hepatite C Crônica
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Quimioterapia Combinada
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República da Coreia
Limite:
Female
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2016
Tipo de documento:
Article