Correlations of endoplasmic reticulum stress and cancer drug resistance / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 461-464, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-465653
Biblioteca responsável:
WPRO
ABSTRACT
Endoplasmic reticulum is an important organelle in eu-karyotic cells.Endoplasmic reticulum stress (ERS)is usually triggered under cell hypoxia,carbohydrate undersupply or medi-cal treatment.Now,present studies show that ERS could activate several cell signal pathways and the UPR pathway is most widely researched.When UPR activates cell signal pathway,it can reg-ulate cancer drug resistance by involving with DNA damage re-pair,apoptotic suppression and autophagy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmacological Bulletin
Ano de publicação:
2015
Tipo de documento:
Artigo