Second trimester cervical length measurement for prediction spontaneous preterm birth in an unselected risk population
Obstetrics & Gynecology Science
; : 329-335, 2017.
Article
em En
| WPRIM
| ID: wpr-46655
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To assess the predictive capacity of cervical length (CL) measurement underwent during the second trimester ultrasound for prediction preterm birth <32, 34, and 37 weeks of gestation in an unselected risk population.METHODS:
A retrospective cohort study was performed with 751 singleton pregnancies between 20 and 24+6 weeks of gestation. The CL measurement (mm) using the transvaginal route was obtained in a sagittal view and the calipers positioned to measure the linear distance between the triangular area of echodensity at the external os and the internal os. To compare the preterm (<37 weeks) and term births (≥37 weeks), we used unpaired t test. We assessed whether the CL measurement was dependent of gestational age by performing a linear regression and assessing the coefficient of determination (R²). We additionally assessed the accuracy of CL measurement to predict preterm birth by assessing the area under receiver operating characteristics curves with its respective confidence intervals (CIs) 95%.RESULTS:
Preterm birth <37 weeks was found in 13.6% (102/751) of pregnant women. Short cervix (≤25 mm) was found in 2.7% (20/751) of pregnancies. Only 30% (6/20) of pregnant women with short cervix have used progesterone to prevent preterm birth. There was a weak correlation between CL measurement and gestational age at delivery (R²=0.01, P=0.002). Receiver operating characteristics curve analysis of the ability of CL measurement to predict preterm birth <32, 34, and 37 weeks, showed an area under the curve of 0.693 (95% CI, 0.512 to 0.874), 0.472 (95% CI, 0.353 to 0.591), 0.490 (95% CI, 0.426 to 0.555), respectively.CONCLUSION:
There was a weak correlation between CL measurement and gestational age at delivery. In an unselected population, CL measurement screening at 20 to 24+6 weeks of gestation does not seem to be a good predictor of preterm birth.Palavras-chave
Texto completo:
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Base de dados:
WPRIM
Assunto principal:
Segundo Trimestre da Gravidez
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Progesterona
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Modelos Lineares
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Colo do Útero
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Programas de Rastreamento
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Estudos Retrospectivos
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Curva ROC
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Estudos de Coortes
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Ultrassonografia
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Idade Gestacional
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
/
Screening_studies
Limite:
Female
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Humans
/
Pregnancy
Idioma:
En
Revista:
Obstetrics & Gynecology Science
Ano de publicação:
2017
Tipo de documento:
Article