The expression of MiR-34a/c in lesions of psoriasis vulgaris Uyghur and Han patients in XinJiang / 中国医师杂志
Journal of Chinese Physician
; (12): 1658-1661, 2015.
Article
em Zh
| WPRIM
| ID: wpr-490562
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WPRO
ABSTRACT
Objective To investigate the expression differences of MiR-34a/c in lesions of psoriasis vulgaris Uyghur and Han patients and beside-lesional tissue and normal skin tissue in XinJiang.Methods Real-time fluorescent quantitative polymerase chain reaction (PCR) was used to determine the expression levels of MiR-34a/c in the psoriasis vulgaris Uyghur and Han patients with lesion tissues, beside-lesion tissues, and normal skin tissues, respectively.Results The expression level of MiR-34a was higher in lesions of psoriasis vulgaris in XinJiang than in the beside-lesion tissues and normal skin tissues, and differences were statistical significance (P < 0.05).However, the expression level of MiR-34a in beside-lesion tissues and normal skin tissues, and in the Uyghur and Han psoriasis vulgaris werent statistically significant difference (P > 0.05).The expression level of MiR-34c in three types of tissues and in the Uyghur and Han psoriasis vulgaris weren't statistically significant difference (P > 0.05).Conclusions MiR-34a might participate in the pathogenesis of Uyghur and Han psoriasis vulgaris in XinJiang.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Chinese Physician
Ano de publicação:
2015
Tipo de documento:
Article