Analysis of Drug Resistance Characteristics of Imipenem-resistant Pseudomonas aeruginosa and Infection Risk Factors in Zhoushan Area / 中国药房
China Pharmacy
; (12): 1061-1063, 2016.
Article
em Zh
| WPRIM
| ID: wpr-501355
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To provide reference for imipenem-resistant Pseudomonas aeruginosa infection control.METHODS:
114 patients infected with imipenem-resistant P. aeruginosa were selected from 3 tertiary hospitals in Zhoushan during Feb. 2013 to Feb. 2014. 114 strains of P. aeruginosa were isolated from clinical specimens,and drug resistance characteristics and carbapene-mase-producing gene diversity were analyzed. 101 inpatients with imipenem-resistant P. aeruginosa infection were included in con-trol group;univariate and multivariate Logistic regression analysis were adopted to explore the risk factors of imipenem-resistant P. aeruginosa infection.RESULTS:
114 strains were sensitive to polymyxin B,and had different levels of resistance to other 9 kinds of antibiotics. Carbapenemase-producing gene were mainly IMP and VIM type gene. Long-term hospitalization,mechanical ventila-tion,used imipenem and early combined use of antibiotics were risk factors of imipenem-resistant P. aeruginosa infection. CON-CLUSIONSIn Zhoushan area,imipenem-resistant P. aeruginosa shows serious drug resistance. To avoid long-term hospitalization and early combined use of antibiotics can reduce imipenem-resistant P. aeruginosa infection.
Texto completo:
1
Base de dados:
WPRIM
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
2016
Tipo de documento:
Article