Effect of Saponins Ⅰ Extracted from Paris Polyphylla on Coronary Artery Endothelial Cell Proliferation / 昆明医科大学学报
Journal of Kunming Medical University
; (12): 37-40, 2016.
Article
em Zh
| WPRIM
| ID: wpr-509759
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the effect of ParidissaponinⅠ (PSⅠ) on the proliferation of coronary artery endothelial cells (CAECs).Methods CAECs were cultured with PSⅠ.CAEC growth rate was calculated by using blood cell counting plate.Cell viability was measured by MTT.The expressions of cadherin and caspase3 mRNA were detected by RT-PCR.Results PSⅠ slowed down growth rate of CAECs,reduced cell viability of CAECs,decreased the expression of cadherin mRNA and increased the expression of caspase3 mRNA in CAECs.Conclusion PSⅠ inhibits the proliferation of CAECs and induces CAECs apoptosis.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Kunming Medical University
Ano de publicação:
2016
Tipo de documento:
Article
País de publicação:
CHINA
/
CN
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REPUBLIC OF CHINA