EXPERIMENTAL SYUDY ON ISOLATION AND CLEAN-UP SYNTHETIC PYRETHROID INSECTICIDES FROM BIOLOGICAL SAMPLES WITH SOLID PHASE EXTRACTION / 中国法医学杂志

ABSTRACT

A method for simultaneous isolation and clean-up pyrethroid insecticides (methothrin, fenpropathrin,cyhalothrin, permethrin, cypermethrin, fenvalerate and deltamethrin)with a solid phase extractionmethod (Sep-Pak C18 cartridge) from biological samples (human plasma and urine) is presented.The systematic separation of the insecticides was excellently performed by wide-bore capillary gaschromatography with flame ionization detection and temperature programming. The recoveries werebetween 81% and 93% for plasma, and 90% and 102% for urine. Mixing the samples with 70%methanol and eluting with chloroform demonstrated excellent adsorption on C18 and the best recoveries,respectively.