Preparation and Quality Control of Dilute Atropine Sulfate Eye-drops / 中国药房
China Pharmacy
; (12)1991.
Article
em Zh
| WPRIM
| ID: wpr-526728
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To establish the preparation process and method of quality control of dilute atropine sulfate eye-drops.METHODS:
Mixing atropine sulfate with additives in water to prepare 0.04% atropine sulfate eye-drops.And determined the content of atropine sulfate by HPLC,the system consisted of C18 column and mobile phase of acetonitrile-water (55∶45).RESULTS:
The product is colorless and clearing liquid.The linear range of atropine sulfate was 10~60?g/ml(r=0.9 999).The average recovery rate was100.2%(RSD=0.95%,n=9).CONCLUSION:
The preparation process of dilute atropine sulfate eye-drops is simple and the method of quality control by HPLC is reliable.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
China Pharmacy
Ano de publicação:
1991
Tipo de documento:
Article