Cost-Effectiveness Analysis of 3 Drug Regimes for Infection of Helicobacter Pylori / 中国药房

ABSTRACT

OBJECTIVE:To evaluate the cost-effectiveness of three drug regimes for infection of Helicobacter Pylori (Hp).METHODS:150 patients with peptic ulcer infected by positive Hp were randomly assigned to three groups.They were treated with Lansoprazole,Clarithromycin and amoxicillin (group A,n=50),Rabeprazole,amoxicillin and metronidazole (group B,n=50) or omeprazole,Clarithomycin and amoxicillin (group C,n=50),respectively with course of treatment as 7 days.The observation of clinical efficacy and analysis of cost-effectiveness were conducted.RESULTS:In group A,B,C,the costs were 120.19,62.02,120.75 yuan;the eradication of Hp was 82%,92%,80%;ratio of cost-effectiveness was 146.57,67.41,150.94,respectively;incremental costs were 523.50,440.50.CONCLUSION:The regime for Hp in group B is the best one among 3 groups.