Your browser doesn't support javascript.
loading
Clinical Value of Hepatitis Screening and Liver Function Test in Korean Patients with Lichen Planus / 대한피부과학회지
Article em Ko | WPRIM | ID: wpr-53411
Biblioteca responsável: WPRO
ABSTRACT
BACKGROUND: The relationship between viral hepatitis and lichen planus (LP) remains as a matter of controversy. Geographical variations are suggested to be a major factor influencing such association. Reliable figures from Korean patients are still lacking. OBJECTIVE: The aim of this study is to determine the prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in Korean patients with lichen planus (LP) and to compare it with patients without LP. METHODS: The retrospective study was performed on 45 LP patients and 45 controls with matching age and gender. We examined for serological evidences of hepatic disease, hepatitis B surface antigen (HBsAg), and anti-HCV seropositivity. Statistical analysis was calculated by using an unpaired t-test and Fisher's exact test. RESULTS: No significant differences between the serum levels of alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were observed between the two groups. The prevalence of HBsAg in LP patients (4.4%) was not significantly higher (p>0.05) than those of the control subjects (2.2%). None of the patients with LP nor the control subjects had Anti-HCV. CONCLUSION: Korean patients with LP did not have any significant associations with liver diseases or HBV, and HCV infections. Although a large-scale multicenter study is needed to support our results, it is not advisable for Korean patients with LP to be tested for liver functions or HBV, and HCV infections as part of a routine screening test.
Assuntos
Palavras-chave
Texto completo: 1 Base de dados: WPRIM Assunto principal: Aspartato Aminotransferases / Vírus da Hepatite B / Programas de Rastreamento / Prevalência / Estudos Retrospectivos / Hepacivirus / Alanina Transaminase / Hepatite / Antígenos de Superfície da Hepatite B / Líquen Plano Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Screening_studies Limite: Humans Idioma: Ko Revista: Korean Journal of Dermatology Ano de publicação: 2013 Tipo de documento: Article
Texto completo: 1 Base de dados: WPRIM Assunto principal: Aspartato Aminotransferases / Vírus da Hepatite B / Programas de Rastreamento / Prevalência / Estudos Retrospectivos / Hepacivirus / Alanina Transaminase / Hepatite / Antígenos de Superfície da Hepatite B / Líquen Plano Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Screening_studies Limite: Humans Idioma: Ko Revista: Korean Journal of Dermatology Ano de publicação: 2013 Tipo de documento: Article