Expression of hepatitis B virus DNA vaccine in immunized mice / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1985.
Article
em Zh
| WPRIM
| ID: wpr-536676
Biblioteca responsável:
WPRO
ABSTRACT
Objective:To research the expression of HBsAg DNA vaccine in immunized mice.Methods:The expression of HBsAg DNA vaccine was detected by immunohistochemistry staining in muscle fibers,lymphoid nodes and spleens of mice after intramuscular injection.Anti-HBsAg antibody was assayed by ELISA and the proliferation of spleen cells was measured by MTT.Results:The positive expression was observed in the tissues mentioned above.The titer of serum antibody showed positive results.Spleen cells could be proliferated by stimulating with HBsAg or ConA.Conclusion:The positive expression and certain kinds of immune responses have been shown in immunized mice.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Immunology
Ano de publicação:
1985
Tipo de documento:
Article