Difference of T lymphocyte subpopulations between peripheral blood and limbusconjunctiva in Mooren's ulcer / 眼科

ABSTRACT

Using indirect immunofluorescent technique and immunohistochemical staining method,we detected 14 patients with progressive Mooren's ulcer for T lymphocyte suhpopulations(Pan-T,Th,Ts)and the ratio of Th/Ts in peripheral blood as well as in the limbus conjunctiva near the corneal ulcer.It was found that Pan-T,Th,Ts and Th/Ts ratio in con- junctiva were significantly higher than that in normal control,whereas these parameters in peripheral blood showed no differences from that in the control group.From the above data,we may conclude that the intensive immune activities due to the increased local Th/Ts ratio play an important role in the process of Mooren's ulcer.