Comparative investigation into the current therapeutic strategy for community acquired pneumonia with the suggested protocols by national and international guidelines / 中国实用内科杂志

ABSTRACT

Objective To explore the current therapeutic strategy for community acquired pneumonia(CAP) in the tertiary hospitals in Beijing district,and provide the evidence-based medicine for recommending application of Chinese community acquired pneumonia(CAP) guideline in our country widely.Methods The data of 225 hospitalized CAP patients from July 1st,2002 to June 30,2004 was documented retrospectively. The patient's situation was scored by either Chinese CAP guideline or Fine's risk classification.The data was analyzed with SPSS 10.0 to identify the correlation between the results evaluated by the two guidelines,and the differences of the combining use of antibiotics and antibiotic selection between group 1 and group 2 classified by Chinese CAP guideline.Results There was a significantly statistical correlation between the two guidelines(P=0.0000).There was a significantly statistical difference both in alternative administration of single or combining antibiotics(P=0.0290) and alternative application of penicillin or the third generation of cephalosporins(P=0.0001,P=0.005,respectively) between hospitalized criteria mismatched and matched groups classified by Chinese CAP guideline.The ratio of using fluroquinolone in above two groups was significantly high compared with other reagents,and there was no significant difference between them(P=0.182).Conclusion There is significant correlation between Chinese CAP guideline and Fine's risk classification.Chinese CAP guideline can be used to distinguish CAP from different risk levels.It is necessary to enforce and standardize the CAP diagnosis and treatment guideline widely.