Study on the effect of growth hormone and chemotherapy in tumor bcaring micc / 肠外与肠内营养
Parenteral & Enteral Nutrition
; (6)2004.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-559842
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To study the effect of recombinant human growth hormone(rhGH) and its combination with chemotherapy(5-FU) in tumor bearing mice.Methods:
Hepatic metastases model were established in 615 mice by splenic injection of proventriculus squamous carcinoma cell(MFC).Among them,sixty mice were divided randomly into 6 groups(ten per group) control(NS),GH1,GH2,flurouracil(5-FU),flurouracil plus rhGH(GH1+5-FU) and flurouracil plus rhGH(GH2+5-FU).Body weights were measured every week.On the 28~(th) day,animals in each group were executed.The weight of body and liver was measured,and cell cycle of tumor DNA was determined by flow cytometry(FCM). Other 48 animals were divided randomly into 6 groups(eight per group) and treated with the same methods as above.They were fed till death to observe survival time.Results:
Body weights in the GH1+(5-FU) and the GH2+5-FU group were increased than that of control group(P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Parenteral & Enteral Nutrition
Ano de publicação:
2004
Tipo de documento:
Artigo