Gadd45a Function in Suppressing Cell Transformation and Tumor Malignancy / 生物化学与生物物理进展
Progress in Biochemistry and Biophysics
; (12)2006.
Article
em Zh
| WPRIM
| ID: wpr-588113
Biblioteca responsável:
WPRO
ABSTRACT
Gadd45a, a p53 and BRCA1-regulated growth arrest and DNA damage gene, plays important roles in suppressing cell transformation and tumor malignancy. Gadd45a maintains the genomic stability through inhibiting the cell growth and promoting the DNA repair etc, by which it suppresses the tumor development. Additionally, Gadd45a is involved in some important signaling pathway, contributing to its function in tumor suppressing.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Progress in Biochemistry and Biophysics
Ano de publicação:
2006
Tipo de documento:
Article