Neuroprotective effect of Gangliosides on rats with cerebral ischemia-reperfusion / 临床神经病学杂志
Journal of Clinical Neurology
; (6)1992.
Article
em Zh
| WPRIM
| ID: wpr-590990
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WPRO
ABSTRACT
Objective To observe the neuroprotective effect of Gangliosides on rats with cerebral ischemia-reperfusion. Methods Rat models were established through middle cerebral artery occlusion and divided into sham-operation group, ischemia-reperfusion group and Gangliosides group. The volume of infarotion and changes of NAA and Lactate at different time point were evaluated by DWI and MRS examinations. Results The mean infarcted volume measured by DWI at 1 h, 3 h and 6 h after ischemia-reperfusion in Gangliosides group was (30.32?8.18) mm3, (35.17?12.45) mm3 and (31.4?8.56) mm3, respectively, versus (204.6?37.77) mm3, (218.9?67.33) mm3 and (213.4?99. 95) mm3 in ischemia-reperfusion group.There were significant differences between the two groups (allP
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Neurology
Ano de publicação:
1992
Tipo de documento:
Article