Hypometabolism based on a cutoff point on the mini-mental state examination in Parkinson’s disease
Neurology Asia
; : 247-253, 2016.
Article
em En
| WPRIM
| ID: wpr-625387
Biblioteca responsável:
WPRO
ABSTRACT
Objective: The aim of the present study was to evaluate cortical hypometabolism of the F-18- fluorodeoxyglucose positron emission tomography (FDG-PET) based on a diagnostic cutoff point of the mini-mental state examination (MMSE) in de novo PD.Methods: We recruited 24 PD patients and 15 healthy controls to analyze FDG-PET. We divided the patients into two groups by the diagnostic cutoff point of MMSE for diagnosing dementia, with scores of>25 vs. 25. Compared to healthy controls, patients with a MMSE> 25 and 25 and < 25 was found in the right inferior parietal lobule. Conclusions: In the comparison by cutoff point of MMSE (25/24), hypometabolism in the right inferior parietal lobule suggests that the posterior cortical deficit is the main region ofde novo PD with cognitive impairment. Hypometabolism of right inferior parietal lobule is related to the damage of cerebral networkin de novo PD.
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Base de dados:
WPRIM
Assunto principal:
Doença de Parkinson
Idioma:
En
Revista:
Neurology Asia
Ano de publicação:
2016
Tipo de documento:
Article