Extensive myelofibrosis responsive to treatment for acute erythroblastic leukaemia
The Malaysian Journal of Pathology
; : 55-8, 2006.
Article
em Ml
| WPRIM
| ID: wpr-626709
Biblioteca responsável:
WPRO
ABSTRACT
Intense myelofibrosis is rarely associated with de novo acute myeloid leukaemia (AML) except in acute megakaryoblastic leukaemia (AML-M7) where there is diffuse marrow fibrosis as a consequence of proliferation of neoplastic myeloid cells. AML associated with significant myelofibrosis developing both de novo or secondary to primary (idiopathic) myelofibrosis is characterised by a fulminant course and extremely poor prognosis, primarily due to treatment-resistant disease. The prognostic value of degree of marrow fibrosis in de novo AML has been poorly investigated. We describe a case of extensive myelofibrosis associated with acute erythroblastic leukaemia (AML-M6) that responded to induction therapy of the leukaemia.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Leucemia Mieloide Aguda
/
Mielofibrose Primária
Idioma:
Ml
Revista:
The Malaysian Journal of Pathology
Ano de publicação:
2006
Tipo de documento:
Article