A Case of Pheochromocytoma with Ganglioneuronal Differentiation Producing Vasoactive Intestinal Peptide / 대한내분비학회지
Journal of Korean Society of Endocrinology
; : 227-231, 2003.
Article
em Ko
| WPRIM
| ID: wpr-63076
Biblioteca responsável:
WPRO
ABSTRACT
Vasoactive intestinal peptide(VIP) is a 28-amino acid peptide, which may cause secretory diarrhea by stimulating the production of adenylate cyclase. Neuroendocrine tumors, secreting vasoactive intestinal peptide (VIP), are almost always of a pancreatic in origin. However, a pheochromocytoma may produce several neuropeptides, containing VIP, as they are considered to be neuroendocrine tumors. A 57-year-old woman, who presented with chronic watery diarrhea, hypokalemia, weight loss and a left adrenal mass, is described. Histologically, the tumor was diagnosed as a pheoch-romocytoma, with ganglioneuronal differentiation, and was histochemically confirmed to produce a vasoactive intestinal polypeptide. A left adrenal VIP-producing pheochromocytoma was successfully resected. After surgery, her diarrhea subsided and the electrolytes, affected neuroendocrine hormone levels, blood pressure and blood sugar level were normalized.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Feocromocitoma
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Glicemia
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Pressão Sanguínea
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Neuropeptídeos
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Peptídeo Intestinal Vasoativo
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Redução de Peso
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Adenilil Ciclases
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Tumores Neuroendócrinos
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Diarreia
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Eletrólitos
Limite:
Female
/
Humans
Idioma:
Ko
Revista:
Journal of Korean Society of Endocrinology
Ano de publicação:
2003
Tipo de documento:
Article