Influence of Inhaled Corticosteroids on Airway Transforming Growth Factor - ?1 Expression of Asthmatic Remodeling Model / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2003.
Article
em Zh
| WPRIM
| ID: wpr-638581
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the role of inhaled corticosteroids (ICS) on transforming growth factor - ?1 (TGF - ?1 )of asthmatic remodeling model Methods One hundred and eight guinea pigs were divided into 3 groups randomly and equally asthmatic group( A), therapeutic group(B), control group(C) Three groups were treated by ovalbumin, budesonide, normal saline respectively The lung tissue specimens were collected after the guinea pigs were killed; the expression of TGF- ?1 was determined Results The expressions of TGF-?1 in A, K and C groups were(41 83 ? 10. 45) %, (27. 22 ? 8. 09)% , (15. 36 ? 2. 64)% respectively at 12 weeks. It was statistically significant( P
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1
Base de dados:
WPRIM
Tipo de estudo:
Prognostic_studies
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2003
Tipo de documento:
Article