Expression of Livin Gene and Its Isoforms in Children with Gliomas / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2006.
Article
em Zh
| WPRIM
| ID: wpr-639324
Biblioteca responsável:
WPRO
ABSTRACT
Objective To study the expression of novel inhibitor of apoptosis protein(IAP) family member livin gene and its two isoforms(livin ? and livin ?) in brain tissue of children with gliomas.Methods Livin ? and Livin ? mRNA were detected by real time fluorescent quantitative reverse transcription polymerase chain reaction(RT-PCR) in brain tissue of 30 children with gliomas and 12 healthy children.Result The positive rate of Livin mRNA expression was 83.3%(25/30 cases)in 30 cases of children with gliomas,the positive rate of Livin mRNA was only 8.3%(1/12 case) in normal brain tissue,there was significant difference in 2 groups(P
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2006
Tipo de documento:
Article