Pentacam's anterior segment analysis system evaluates the efficacy of Lotemax in controlling postoperative inflammation following cataract surgery / 眼科新进展

ABSTRACT

Objeetive To observe the efficacy and safety of 5 g · L-1 Lotemax suspended eye drops in inflammation control after phacoemulsification combined with intraocular lens implantation.Methods Together 60 patients with senile cataract (grade III or more severe) underwent cataract surgery were selected and randomly divided into two groups,including Lotemax group,in which patients were given 5 g · L-1 Lotemax suspended eye drops and Tobramycin eye drops,and Tobradex group,in which patient were alone given Tobradex eye drops.Corneal edema,anterior chamber flare,corneal volume,anterior chamber volume and corneal incision thickness were observed at 1 day,7 days and 30 days after operation,while intraocular pressure was observed at 7 days and 30 days before and after operation.Then the efficacy of Lotemax in control of postoperative inflammation was evaluated by Pentacam's anterior segment analysis system.Results There was no significant difference in corneal edema,anterior chamber flare,corneal volume,anterior chamber volume and corneal incision thickness between the two groups at postoperative 1 day and 30 days (all P ＞ 0.05),but Tobradex group had weak anterior chamber flare and lower corneal volume than Lotemax group (P =0.029,0.019),while the difference in corneal edema,anterior chamber volume and corneal incision thickness was not statistically significant between two groups at postoperative 7 days (P =0.119,0.138,0.101).Moreover,there was no significant difference in intraocular pressure at 7 days and 30 days before and after surgery between the two groups (all P ＞ 0.05).Conclusion Lotemax suspended eye drops can effectively control the inflammation followed by cataract phacoemulsification combined with intraocular lens implantation.